Children with cerebral palsy (CP) may experience challenges to succeed in their studies due to pain affecting attention in combination with being unable to express pain. Therefore, professionals need knowledge in how to manage the children’s pain in school settings to ensure their optimal participation. It is, however, uncertain how they manage and if there are differences between cultures. The aim of the project was to investigate how professionals manage pain in children with CP in school settings in Sweden and South Africa. Three focus groups in was carried out in South Africa and Sweden respectively. The sample includes teachers, assistants, and health professionals who recently met a child with CP who experienced pain in mainstream or special school. Qualitative content analysis was used and results from the different cultures compared. The results are presented as four separate studies.